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HRID987508

反应详情

EQUATION

反应方程式

HRID 987508 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)OC(=O)N1CCCN(c2ccc([N+](=O)[O-])cc2)CC1
HCID18008978

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCCN(c2ccc(N)cc2)CC1
HCID18008968

tert-Butyl 4-(4-aminophenyl)-1,4-diazepane-1-carboxylate

C16H25N3O2

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

1-Boc-4-(4-nitrophenyl)homopiperazine (prepared with 1-fluoro-4-nitrobenzene, 1-Boc-homopiperazine, Cs2CO3 in heated DMF) was dissolved in methanol. To it was added 10% Pd/C. The slurry was stirred under a hydrogen balloon for 2 hrs. It was filtered through celite and evaporated in vacuuo to give 1-(4-aminophenyl)-4-Boc-homopiperazine. ES-MS: (M+H)+292.

WORKUP

后处理

  1. filtrationIt was filtered through celite
  2. customevaporated in vacuuo