Phenylboronic Acid → HCID 18009272, compound

HRID 987840Notes

Reaction equation

HRID 987840 reaction equation
Br[C:2]1[CH:8]=[C:7]([CH3:9])[CH:6]=[C:5]([CH3:10])[C:3]=1[NH2:4].[C:11]1(B(O)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[NH2:4][C:3]1[C:5]([CH3:10])=[CH:6][C:7]([CH3:9])=[CH:8][C:2]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 1705792-Bromo-4,6-dimethylaniline

Product 1

HCID 18009272HCID 18009272, compound

Procedure

2-Bromo-4,6-dimethylaniline was coupled with phenyl boronic acid under Suzuki conditions to give 2-amino-3,5-dimethylbiphenyl in 68% yleld.

Sources & evidence

ORD record
ord-028fbf11f42d42b0b73bda01b9ea2609
Source dataset
uspto-grants-2003_10
Patent number
US06632829B2

Reaction notes

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