Dichloromethane → 1-[1-(3-chloro-3-phenylpropyl)piperidin-4-yl]-5-(methylsulfonyl)-1H-benzimidazole
Reaction equation
[CH3:1][S:2]([Cl:3])(=[O:4])=[O:5].[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[CH3:6][S:7](=[O:8])(=[O:9])[c:10]1[cH:11][c:12]2[c:13]([n:14]([CH:17]3[CH2:18][CH2:19][N:20]([CH2:23][CH2:24][CH:25]([OH:26])[c:27]4[cH:28][cH:29][cH:30][cH:31][cH:32]4)[CH2:21][CH2:22]3)[cH:15][n:16]2)[cH:33][cH:34]1.[Cl:42][CH2:43][Cl:44]>>[Cl:3][CH:25]([CH2:24][CH2:23][N:20]1[CH2:19][CH2:18][CH:17]([n:14]2[c:13]3[c:12]([cH:11][c:10]([S:7]([CH3:6])(=[O:8])=[O:9])[cH:34][cH:33]3)[n:16][cH:15]2)[CH2:22][CH2:21]1)[c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1Participants
5
Sources & evidence
- ORD record
- ord-5a001caecce3432583c1d78355bfb5b9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…