HRID987941

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)CN([C@H](CO)CCCN)S(=O)(=O)c1ccc(N)cc1

HCID12986160

未命名化合物

结构：COC(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)O

HCID12986162

未命名化合物

PRODUCTS

生成物

结构：COC(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)NCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1

HCID513924

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from general procedure A using (2S)-2-methoxycarbonylamino-3-naphthalen-1-yl-propionic acid and amine intermediate VII. The final product was obtained in 76% yield. Rf=0.57, EtOAc 100%.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c7f58c981ac946319b6c03b59409c41a
来源数据集: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06632816B1
来源说明: uspto-grants-2003_10

反应 SMILES

[CH3:1][O:2][C:3]([NH:5][C@@H:6]([CH2:10][C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][CH:12]=1)[C:7]([OH:9])=O)=[O:4].[NH2:21][C:22]1[CH:27]=[CH:26][C:25]([S:28]([N:31]([C@H:36]([CH2:41][OH:42])[CH2:37][CH2:38][CH2:39][NH2:40])[CH2:32][CH:33]([CH3:35])[CH3:34])(=[O:30])=[O:29])=[CH:24][CH:23]=1>>[CH3:1][O:2][C:3](=[O:4])[NH:5][C@H:6]([C:7](=[O:9])[NH:40][CH2:39][CH2:38][CH2:37][C@H:36]([N:31]([S:28]([C:25]1[CH:24]=[CH:23][C:22]([NH2:21])=[CH:27][CH:26]=1)(=[O:30])=[O:29])[CH2:32][CH:33]([CH3:34])[CH3:35])[CH2:41][OH:42])[CH2:10][C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][CH:12]=1