HRID987945

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)CN([C@H](CO)CCCN)S(=O)(=O)c1ccc(N)cc1

HCID12986160

未命名化合物

结构：O=C(O)[C@@H](NC(=O)N1CCOCC1)C(c1ccccc1)c1ccccc1

HCID12986168

未命名化合物

PRODUCTS

生成物

结构：CC(C)CN([C@H](CO)CCCNC(=O)[C@@H](NC(=O)N1CCOCC1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1

HCID513931

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from general procedure A using (2S)-2-[(morpholine-4-carbonyl)-amino]-3,3-diphenyl-propionic acid and amine intermediate VII. The final product was obtained in 36% yield. Rf=0.15 EtOAc 100%.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-30b78349ba55459aa32aa504198a84de
来源数据集: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06632816B1
来源说明: uspto-grants-2003_10

反应 SMILES

[N:1]1([C:7]([NH:9][C@@H:10]([CH:14]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:11](O)=[O:12])=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[NH2:27][C:28]1[CH:33]=[CH:32][C:31]([S:34]([N:37]([C@H:42]([CH2:47][OH:48])[CH2:43][CH2:44][CH2:45][NH2:46])[CH2:38][CH:39]([CH3:41])[CH3:40])(=[O:36])=[O:35])=[CH:30][CH:29]=1>>[NH2:27][C:28]1[CH:33]=[CH:32][C:31]([S:34]([N:37]([CH2:38][CH:39]([CH3:41])[CH3:40])[C@H:42]([CH2:47][OH:48])[CH2:43][CH2:44][CH2:45][NH:46][C:11]([C@@H:10]([NH:9][C:7]([N:1]2[CH2:2][CH2:3][O:4][CH2:5][CH2:6]2)=[O:8])[CH:14]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:12])(=[O:36])=[O:35])=[CH:30][CH:29]=1