HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-1H-imidazole-4-carbaldehyde → HCID 178433224, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-1H-imidazole-4-carbaldehyde | HCID 2795887 | — |
| Reactant | 4-Pyridin-4-yl-1,3-dihydro-indol-2-one | HCID 12111581 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178433224 | HCID 178433224 | 10.7% |
Reaction Steps
A mixture of 4-pyridin-4-yl-1,3-dihydroindol-2-one (50 mg, 0.24 mmol), 5-methyl-3H-imidazole-4-carbaldehyde (24.4 mg, 0.24 mmol) and piperidine (1 drop) in ethanol (2 mL) was stirred at room temperature for 2 days. The precipitate which formed was filtered. Crystals which formed in the filtrate were isolated, washed with ethanol and dried to give 7.8 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06635640B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-6992c1d77eb849498f8887999c10896b |
| Source note | uspto-grants-2003_10 |