Hydrogen Bromide → HCID 18007940, compound

HRID 988233Notes

Reaction equation

HRID 988233 reaction equation
Br.C[O:3][C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[CH:9][CH:10]=[C:11]2[CH2:14][C:15]([OH:17])=[O:16])=[CH:6][CH:5]=1>C(O)(=O)C>[OH:3][C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[CH:9][CH:10]=[C:11]2[CH2:14][C:15]([OH:17])=[O:16])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 135701052-(7-Methoxynaphthalen-1-yl)acetic acid

Product 1

HCID 18007940HCID 18007940, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In a 250 ml round-bottomed flask, dissolve 2-(7-methoxynaphth-1-yl)acetic acid in acetic acid. Add hydrobromic acid and reflux the reaction mixture for 4 hours. Remove the acetic acid and hydrobromic acid by evaporation under reduced pressure. Take up the solid in water and suction it off. Wash the precipitate with petroleum ether and recrystallise it from toluene.

Workup

  1. customRemove the acetic acid and hydrobromic acid
  2. customby evaporation under reduced pressure
  3. washWash the precipitate with petroleum ether
  4. customrecrystallise it from toluene

Sources & evidence

ORD record
ord-6d78c4390c6245dca914947d9e6d8e6f
Source dataset
uspto-grants-2003_10
Patent number
US06635650B2

Reaction notes

Loading…