Isopropanol → propan-2-yl 4-[[3,5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-8-bromo-2-cyclopropyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinoline-1-carboxylate
Reaction equation
[C:1]([Cl:2])([Cl:3])=[O:4].[CH:46]([CH3:47])([CH3:48])[OH:49].[F:5][C:6]([c:7]1[cH:8][c:9]([CH2:10][N:11]([CH:12]2[CH2:13][CH:14]([CH:30]3[CH2:31][CH2:32]3)[N:15]([C:27](=[O:28])[OH:29])[c:16]3[c:17]([Br:26])[cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][c:21]32)[C:33](=[O:34])[O:35][CH3:36])[cH:37][c:38]([C:40]([F:41])([F:42])[F:43])[cH:39]1)([F:44])[F:45]>>[F:5][C:6]([c:7]1[cH:8][c:9]([CH2:10][N:11]([CH:12]2[CH2:13][CH:14]([CH:30]3[CH2:31][CH2:32]3)[N:15]([C:27]([O:28][CH:46]([CH3:47])[CH3:48])=[O:29])[c:16]3[c:17]([Br:26])[cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][c:21]32)[C:33](=[O:34])[O:35][CH3:36])[cH:37][c:38]([C:40]([F:41])([F:42])[F:43])[cH:39]1)([F:44])[F:45]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-39fbbea72dc14cafab3f4f8c30cdc6d5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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