反应详情

2 g (6.48 mole) of (±)-(2-chlorophenyl)-(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetamide of formula (IV), was dissolved in 10 mL acetone. To the reaction mixture 1 mL of sulfuric acid was added and was stirred for 0.5 hr. Later 5 mL of diethyl ether was added and stirred overnight at room temperature to obtain a salt. The salt 2 g (76%) was isolated by filtration and washed with acetone.

1. stirringstirred overnight at room temperature
2. customto obtain a salt