反应详情

10 g of (+) Methyl (2-chlorophenyl)-(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate prepared according to Example 22, was dissolved in 100 mL of ice-cold acetone and 2 mL concentrated sulfuric acid was added at 0° C. to 5° C. The crystalline white to off white product formed was isolated by filtration and washed with 20 mL of acetone. The product obtained was dried in vacuum oven at 50° C. The yield of titled product was 7.2 g (56%).

1. customThe crystalline white to off white product formed
2. customwas isolated by filtration
3. washwashed with 20 mL of acetone
4. customThe product obtained
5. customwas dried in vacuum oven at 50° C