1-Bromo-2-butanone → 2-Oxobutyl-thiacyclohexanium bromide

HRID 988944Notes

Reaction equation

HRID 988944 reaction equation
[CH2:1]1[S:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:7][CH2:8][C:9](=[O:12])[CH2:10][CH3:11]>CC(C)=O>[Br-:7].[O:12]=[C:9]([CH2:10][CH3:11])[CH2:8][S+:6]1[CH2:5][CH2:4][CH2:3][CH2:2][CH2:1]1

Participants

4

Reactant 2

HCID 131561-Bromo-2-butanoneHCID 15367Thiane

Product 1

HCID 857879522-Oxobutyl-thiacyclohexanium bromideYield 72.7%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The synthesis was carried out under radiation from a yellow lamp. A 100-millilitter three-port flask was prepared. Using the flask, 4 grams of pentamethylenesulfide was dissolved in 40 milli-litter of acetone. 6 grams of 1-bromo-2-butanone was dropped into the solution over agitation. After 24 hours, white crystal was precipitated, and was filtrated. The white crystal was pulverized, and the pulverized white crystal was washed in ether. The resultant crystal was dried by using a low-pressure drier at 30 degrees in centigrade for six hours. Then, 7.2 grams of 2-oxobutyl-thiacyclohexanium bromide was obtained. The yield was 72.5%.

Workup

  1. customThe synthesis was carried out under radiation from a yellow lamp
  2. customA 100-millilitter three-port flask was prepared
  3. customwhite crystal was precipitated
  4. filtrationwas filtrated
  5. washthe pulverized white crystal was washed in ether
  6. customThe resultant crystal was dried
  7. customdrier at 30 degrees
  8. customfor six hours

Sources & evidence

ORD record
ord-0566b95d821a4fccafa2c812b7f7b987
Source dataset
uspto-grants-2003_10
Patent number
US06638685B2

Reaction notes

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