1-Propanol → HCID 87079497, compound

HRID 988981Notes

Reaction equation

[CH2:1]([OH:4])[CH2:2][CH3:3].S(Cl)([Cl:7])=O.[NH2:9][C@H:10]([C:12](O)=[O:13])[CH3:11]>>[ClH:7].[CH2:1]([O:4][C:12](=[O:13])[C@H:10]([CH3:11])[NH2:9])[CH2:2][CH3:3]

Participants

Reactant 3

HCID 10311-Propanol

HCID 5950L-Alanine

HCID 24386Thionyl Chloride

Product 1

HCID 87079497HCID 87079497, compoundYield 94.6%

Procedure

This was synthesised according to Standard Procedure 1, using anhydrous propan-1-ol (42.0 ml, 0.56 mol), thionyl chloride (8.2 ml, 0.112 mol) and L-alanine (5.0 g, 0.056 mol). The product was isolated as a white solid (8.88 g, 94.3%).

Workup

customThis was synthesised

Sources & evidence

ORD record: ord-bedf37e60c5e47a39bd15c16f9773685
Source dataset: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06638919B2

Reaction notes

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