L-Alanine → HCID 88075809, compound

HRID 988982Notes

Reaction equation

[CH2:1]([OH:6])[CH2:2][CH2:3][CH2:4][CH3:5].S(Cl)([Cl:9])=O.[NH2:11][C@H:12]([C:14](O)=[O:15])[CH3:13]>>[ClH:9].[CH2:1]([O:6][C:14](=[O:15])[C@H:12]([CH3:13])[NH2:11])[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

Reactant 3

HCID 5950L-Alanine

HCID 62761-Pentanol

HCID 24386Thionyl Chloride

Product 1

HCID 88075809HCID 88075809, compoundYield 73.7%

Procedure

This was synthesised according to Standard Procedure 1, using pentanol (36.3 ml, 0.337 mol), thionyl chloride (4.92 ml, 67.4 mmol) and L-Alanine (3.0 g, 33.7 mmol). The product was isolated as a white solid pure product (4.86 g, 73.7%).

Workup

customThis was synthesised

Sources & evidence

ORD record: ord-420bc44dc8104f49906718b2e13a771c
Source dataset: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06638919B2

Reaction notes

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