2,3-Dichlorobenzaldehyde → HCID 18004774, compound

HRID 988992Notes

Reaction equation

HRID 988992 reaction equation
[NH2:1][C:2]1[CH:7]=[N:6][CH:5]=[CH:4][N:3]=1.[CH2:8]([N+:12]#[C-:13])[CH2:9][CH2:10][CH3:11].[Cl:14][C:15]1[C:22]([Cl:23])=[CH:21][CH:20]=[CH:19][C:16]=1[CH:17]=O>Cl(O)(=O)(=O)=O>[CH2:8]([NH:12][C:13]1[N:3]2[CH:4]=[CH:5][N:6]=[CH:7][C:2]2=[N:1][C:17]=1[C:16]1[CH:19]=[CH:20][CH:21]=[C:22]([Cl:23])[C:15]=1[Cl:14])[CH2:9][CH2:10][CH3:11]

Participants

5

Reactant 3

HCID 357452,3-DichlorobenzaldehydeHCID 76008Butyl isocyanideHCID 78747Aminopyrazine

Product 1

HCID 18004774HCID 18004774, compound

Reagents, catalysts & solvents 1

HCID 24247Perchloric AcidSolvent

Procedure

Compound (11) was prepared in accordance with general instructions 1 from 1.0 ml aminopyrazine solution (0.1 M, MC), 0.575 ml n-butylisonitrile solution (0.2 M, MC), 0.500 ml 2,3-dichlorobenzaldehyde solution (0.3 M, MC), and 10 μl perchloric acid (w=20%).

Sources & evidence

ORD record
ord-5f2c68babb294dc69e2201e536af92a8
Source dataset
uspto-grants-2003_10
Patent number
US06638933B2

Reaction notes

Loading…