2-Thiophenecarboxaldehyde → HCID 860274, compound

HRID 988999Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[C:8]([N+:12]#[C-:13])([CH3:11])([CH3:10])[CH3:9].[S:14]1[CH:18]=[CH:17][CH:16]=[C:15]1[CH:19]=O.Cl(O)(=O)(=O)=O>>[C:8]([NH:12][C:13]1[N:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]2=[N:1][C:19]=1[C:15]1[S:14][CH:18]=[CH:17][CH:16]=1)([CH3:11])([CH3:10])[CH3:9]

Participants

Reactant 4

HCID 73642-Thiophenecarboxaldehyde

HCID 104392-Aminopyridine

HCID 23577Tert-Butyl isocyanide

HCID 24247Perchloric Acid

Product 1

HCID 860274HCID 860274, compound

Procedure

Compound (23) was prepared in accordance with general instructions 2 from 2-aminopyridine, tert-butylisonitrile, thiophene-2-carbaldehyde, and perchloric acid.

Sources & evidence

ORD record: ord-75455ec80cff4dc4b93519c1c3572200
Source dataset: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06638933B2

Reaction notes

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