Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Urea → 5-Methylthio-6-trifluoromethyl-1-(3-ethoxycarbonylphenyl carbamoyl)-indoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Urea | HCID 1176 | — |
| 반응물 | Ethyl 3-aminobenzoate | HCID 11400 | — |
| 반응물 | Bis-(1H-imidazol-2-YL)-methanone | HCID 5250894 | — |
| 반응물 | HCID 10657270 | HCID 10657270 | — |
| 생성물 | 5-Methylthio-6-trifluoromethyl-1-(3-ethoxycarbonylphenyl carbamoyl)-indoline | HCID 18005160 | 74% |
반응 단계
This was prepared in 74% yield by urea formation between ethyl 3-aminobenzoate and 5-methylthio-6-trifluoromethyl indoline, (D7) using carbonyl diimidazole as the coupling agent.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06638953B2 |
| 출처 데이터셋 | uspto-grants-2003_10 |
| ORD ID | ord-8706c2ec94384d1796f9b5149ec03087 |
| 출처 메모 | uspto-grants-2003_10 |