(Ethylsulfonyl)ethene → HCID 73415474, compound

HRID 989230Notes

Reaction equation

HRID 989230 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[C:12]([Cl:13])=[CH:11][C:10]([C:14]([F:17])([F:16])[F:15])=[CH:9][C:8]=2[Cl:18])[N:5]=[C:4]([CH:19]=[N:20][OH:21])[C:3]=1[S:22]([CH3:24])=[O:23].[O-]CC.[Na+].[CH:29]([S:31]([CH2:34][CH3:35])(=O)=[O:32])=[CH2:30]>C(O)C>[CH2:29]([S:31]([CH2:34][CH2:35][O:21][N:20]=[CH:19][C:4]1[C:3]([S:22]([CH3:24])=[O:23])=[C:2]([NH2:1])[N:6]([C:7]2[C:12]([Cl:13])=[CH:11][C:10]([C:14]([F:17])([F:16])[F:15])=[CH:9][C:8]=2[Cl:18])[N:5]=1)=[O:32])[CH3:30]

Participants

5

Reactant 3

HCID 74680(Ethylsulfonyl)etheneHCID 2723922Sodium ethoxideHCID 1363524165-amino-1-[2,6-dichloro-4-(trifluoromethyl)-phenyl]-4-methylsulfinyl-1H-pyrazole-3-carboxaldehyde oxime

Product 1

HCID 73415474HCID 73415474, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a manner similar to that employed in Example 12 an ethanol solution of 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-methylsulfinyl-1H-pyrazole-3-carboxaldehyde oxime was reacted with sodium ethoxide and ethyl vinyl sulfone to give 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-methylsulfinyl-1H-pyrazole-3-carboxaldehyde O-[2-(ethylsulfinyl)ethyl]oxime, m.p.144-148° C. Compound 27.

Sources & evidence

ORD record
ord-d10a76c3c2844ab1814261c451b231e7
Source dataset
uspto-grants-2003_10
Patent number
US06638956B2

Reaction notes

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