Formaldehyde → HCID 11321022, compound

HRID 989432Notes

Reaction equation

HRID 989432 reaction equation
[NH:1]([CH2:3][CH2:4][OH:5])[NH2:2].Cl[C:7]([O:9][CH3:10])=[O:8].[CH2:11]=O>>[CH3:10][O:9][C:7]([N:1]1[CH2:3][CH2:4][O:5][CH2:11][NH:2]1)=[O:8]

Participants

4

Reactant 3

HCID 712FormaldehydeHCID 6586Methyl chloroformateHCID 80172-Hydrazinoethanol

Product 1

HCID 11321022HCID 11321022, compound

Procedure

The reaction described in the scheme below is an example for the preparation of the compound I where, starting from 2-hydrazinoethanol and methyl chloroformate as acid derivative, firstly N-amino-N-methoxycarbonyl-2-hydrazinoethanol is prepared, which is cyclized in a subsequent reaction with formaldehyde to give tetrahydro-4-methoxycarbonyl-4H-1-oxa-3,4-diazine.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-8d03d07a061b4a1eb1970cd91a36784b
Source dataset
uspto-grants-2003_10
Patent number
US06639070B1

Reaction notes

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