1,4-Dioxane → (3-Chloro-benzyl)-{6-[4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-amine

HRID 98948Notes

Reaction equation

HRID 98948 reaction equation
[CH2:27]([CH3:28])[N:29]1[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]1.[Cl:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][c:7]2[c:8]3[c:9]([n:10][cH:11][n:12]2)[nH:13][c:14](-[c:16]2[cH:17][cH:18][c:19]([CH2:22][Cl:23])[cH:20][cH:21]2)[cH:15]3)[cH:24][cH:25][cH:26]1.[O:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][c:7]2[c:8]3[c:9]([n:10][cH:11][n:12]2)[nH:13][c:14](-[c:16]2[cH:17][cH:18][c:19]([CH2:22][N:32]4[CH2:31][CH2:30][N:29]([CH2:27][CH3:28])[CH2:34][CH2:33]4)[cH:20][cH:21]2)[cH:15]3)[cH:24][cH:25][cH:26]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 791961-EthylpiperazineHCID 69179730(3-Chloro-benzyl)-[6-(4-chloromethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine

Product 1

HCID 69179519(3-Chloro-benzyl)-{6-[4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-amine

Sources & evidence

ORD record
ord-288f3f897c4945c19d0fca856c87a904
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…