HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 2753178, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178441161 | HCID 178441161 | — |
| Product | HCID 2753178 | HCID 2753178 | 29% |
Reaction Steps
2-Amino-5-butyl-6-methylpyrimidine-4-ol (1.0 g, 5.52 mmol) and phosphorus oxychloride (12 ml) were refluxed for 3 hours. The solvent was removed in vacuo and the residue was purified by silica gel column chromatography(n-hexane: ethyl acetate=2:1) to give the object compound (325 mg, 29%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458798B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-67e2d5589a28437cb12f31a8139ee0ca |
| Source note | uspto-grants-2002_10 |