Phosphorus oxychloride → HCID 22313253, compound

HRID 989715Notes

Reaction equation

HRID 989715 reaction equation
[NH2:1][C:2]1[N:3]=[C:4](O)[C:5]2[CH2:11][O:10][CH2:9][CH2:8][C:6]=2[N:7]=1.P(Cl)(Cl)([Cl:15])=O>>[Cl:15][C:4]1[C:5]2[CH2:11][O:10][CH2:9][CH2:8][C:6]=2[N:7]=[C:2]([NH2:1])[N:3]=1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 178508881HCID 178508881, compound

Product 1

HCID 22313253HCID 22313253, compoundYield 22%

Procedure

By reacting 2-amino-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine-4-ol (562 mg, 3.36 mmol) and phosphorous oxychloride (3 ml), there was obtained the object compound (136 mg, 22%).

Sources & evidence

ORD record
ord-5ca052e6139b4946bb982e244e03a0dc
Source dataset
uspto-grants-2002_10
Patent number
US06458798B1

Reaction notes

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