HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl alpha-benzylacetoacetate → HCID 178433370, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl alpha-benzylacetoacetate | HCID 246929 | — |
| Reactant | Carbonic acid-guanidine (1:1) | HCID 286947 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178433370 | HCID 178433370 | — |
Reaction Steps
A mixture of ethyl 2-benzyl-3-oxobutanoate (6 g, 27.2 mmol), guanidine carbonate (2.94 g, 16.3 mmol) and ethanol (20 ml) was refluxed for 10 hours. After cooling, the precipitate was filtered and washed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458798B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-5332110f54a446c096392bcf4a531351 |
| Source note | uspto-grants-2002_10 |