HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 22035746, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-Hydroxyisobutyric acid | HCID 11671 | — |
| Reactant | 4-Methyloxybenzyl chloride | HCID 69993 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22035746 | HCID 22035746 | — |
Reaction Steps
2-hydroxy isobutyric acid (1.56 g) was esterified by alkylation with 4-methoxybenzyl chloride by the method described in Example A-I-1, step a). The title compound (2.65 g) was obtained after silica gel column chromatography (0, 1, 2% ethanol in dichloromethane). Rf (2%MeOH/CHCl3) 0.45.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06458772B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-9312de923c69468ebce16aa06cfac8d9 |
| Source note | uspto-grants-2002_10 |