Pyrrole → 1-[(3-Bromo-2-thienyl)sulfonyl]-1H-pyrrole

HRID 990053Notes

Reaction equation

HRID 990053 reaction equation
[Br:1][C:2]1[CH:6]=[CH:5][S:4][C:3]=1[S:7](Cl)(=[O:9])=[O:8].[NH:11]1[CH:15]=[CH:14][CH:13]=[CH:12]1>>[Br:1][C:2]1[CH:6]=[CH:5][S:4][C:3]=1[S:7]([N:11]1[CH:15]=[CH:14][CH:13]=[CH:12]1)(=[O:9])=[O:8]

Participants

3

Reactant 2

HCID 8027PyrroleHCID 136755983-Bromothiophene-2-sulfonyl chloride

Product 1

HCID 234455281-[(3-Bromo-2-thienyl)sulfonyl]-1H-pyrrole

Procedure

N-(3-Bromothiophene-2-sulfonyl)pyrrole was prepared in the same manner as described in Example 14A by reacting 3-bromothiophene-2-sulfonyl chloride with pyrrole (for 16 hr). N-(3-Bromothiophene-2-sulfonyl)pyrrole was obtained in 54% yield.

Workup

  1. customN-(3-Bromothiophene-2-sulfonyl)pyrrole was prepared in the same manner

Sources & evidence

ORD record
ord-3ffc3f6df482464f8a52215634252f3a
Source dataset
uspto-grants-2002_10
Patent number
US06458805B2

Reaction notes

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