Potassium Hydroxide → HCID 18419672, compound

Participants

Reaction Steps

The compound of step (ii) (225 g) was dissolved by adding portions of 15-20 g to concentrated nitric acid (10M, 500 ml) on an ice bath with stirring. The mixture was stirred for 1 hr and poured onto an ice-cold solution of KOH (600 g) with continuous addition of ice. Then the reaction mixture was divided into 4 portions and each portion of 500 ml was extracted with 300 ml of chloroform. The combined organic layers were dried with anhydrous sodium sulfate and then evaporated in vacuo to give the title compound.

Provenance & Evidence