Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl- → HCID 18418681, compound

Participants

Reaction Steps

N-[4,4-Bis-(4-fluoro-phenyl)-butyl]-2-methylamino-acetamide was prepared in accordance with the methods of Example 12, except that N-tert-butoxycarbonyl-N-methyl-glycine was used instead of N-tert-butoxycarbonyl-N-methyl-L-leucine in Step A, and {[4,4-bis-(4-fluoro-phenyl)-butylcarbamoyl]-methyl}-methyl-carbamic acid tert-butyl ester was used instead of (S)-1-[4,4-bis-(4-fluoro-phenyl)-butylcarbamoyl]-3-methyl-butyl}-methyl-carbamic acid tert-butyl ester in Step B. MS: 333.2 (M+1 for C19H22N2F2O1); an oil;

Provenance & Evidence