Ammonia → HCID 18416850, compound

HRID 991055Notes

Reaction equation

HRID 991055 reaction equation
C([O:3][C:4](=[O:26])[CH:5]([S:7]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][S:18]([CH:21]([C:23]([OH:25])=[O:24])[CH3:22])(=[O:20])=[O:19])(=[O:9])=[O:8])[CH3:6])C.[OH-].[Na+].N>C(O)C>[C:23]([CH:21]([S:18]([CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][S:7]([CH:5]([CH3:6])[C:4]([OH:26])=[O:3])(=[O:9])=[O:8])(=[O:20])=[O:19])[CH3:22])([OH:25])=[O:24]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 14798Sodium HydroxideHCID 54443426HCID 54443426, compound

Product 1

HCID 18416850HCID 18416850, compoundYield 23%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-[8-(1-Carboxy-ethanesulfonyl)-octane-1-sulfonyl]-propionic acid was prepared according to general method as outline in example 1. Starting from 2-[8-(1-carboxy-ethanesulfonyl)-octane-1-sulfonyl]-propionic acid ethyl ester (3.0 g, 6.8 mmol), ethanol (15 mL) and 10 N sodium hydroxide (15 mL). Yield 2.7 g (98%); white solid mp 99-102° C.; MS 387 (M+NH3)+.

Sources & evidence

ORD record
ord-9ed7aaa63c654484b4387d289e354d04
Source dataset
uspto-grants-2002_10
Patent number
US06462073B2

Reaction notes

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