2-(4-Methoxy-phenylsulfanyl)heptanoic acid ethyl ester → HCID 18416776, compound

HRID 991079Notes

Reaction equation

HRID 991079 reaction equation
C([O:3][C:4](=[O:20])[CH:5]([S:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])C>CO.[OH-].[Na+]>[CH3:19][O:18][C:15]1[CH:14]=[CH:13][C:12]([S:11][CH:5]([CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[C:4]([OH:20])=[O:3])=[CH:17][CH:16]=1

Participants

4

Reactant 1

HCID 543572462-(4-Methoxy-phenylsulfanyl)heptanoic acid ethyl ester

Product 1

HCID 18416776HCID 18416776, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

2-(4-Methoxy-phenylsulfanyl)-heptanoic acid was prepared starting with 2-(4-methoxy-phenylsulfanyl)-heptanoic acid ethyl ester (4 g, 13.5 mmol) dissolved in methanol (300 ml) and 10N NaOH (25 ml). The resulting reaction mixture was worked up as outlined in example 1. Yield 3 g (83%). yellow oil. MS: 267.1 (M−H)−.

Workup

  1. customThe resulting reaction mixture

Sources & evidence

ORD record
ord-42fe8787b9db4d1483389ede32d026a6
Source dataset
uspto-grants-2002_10
Patent number
US06462073B2

Reaction notes

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