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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 991272Generated: October 26, 2026

L-Ornithine, 2-(difluoromethyl)-, monohydrochloride → L-Eflornithine

https://huagongshe.com/reaction/991272

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Ornithine, 2-(difluoromethyl)-, monohydrochlorideHCID 23393214—
SolventMethanolHCID 887—
ProductL-EflornithineHCID 6992039—

Reaction Steps

From the evaporated mother liquor of the resolution from Example 1, according to the process described above, (+)-α-difluoromethylornithine monohydrochloride monohydrate was isolated with an optical rotation of [α]20D=+3.1° (c=7.0 in MeOH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06462229B1
Source datasetuspto-grants-2002_10
ORD IDord-7a578809266b44528f6032f2f200a96c
Source noteuspto-grants-2002_10