HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperonal → 1-Isopropyl-6,7-methylenedioxy-4-(3,4-methylenedioxyphenyl)-3,4-dihydroquinazolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperonal | HCID 8438 | — |
| Reactant | 1-(1,3-Benzodioxol-5-yl)-1-isopropylurea | HCID 100555 | — |
| Product | 1-Isopropyl-6,7-methylenedioxy-4-(3,4-methylenedioxyphenyl)-3,4-dihydroquinazolin-2(1H)-one | HCID 12789477 | 41% |
Reaction Steps
The title compound was synthesized from N-isopropyl-N-[3,4-(methylenedioxy)phenyl]urea and piperonal by the procedure described in example 10 in 41% yield, mp: 87-89° C. 1H NMR (CDCl3,): 6.77 (s, 3H), 6.68 (s, 1H), 6.28 (s, 1H), 5.96 (s, 2H), 5.92-5.90 (m, 2H), 5.22 (d, J=1.8, 1H), 4.98 (br s, 1H), 4.44 (m, 2H), 1.58-1.54 (m, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465472B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-5aec52976ddf459cbd1fbdfde1ce0d3a |
| Source note | uspto-grants-2002_10 |