1-(1,3-Benzodioxol-5-yl)-1-isopropylurea → 1-Isopropyl-6,7-methylenedioxy-4-(2-chloro-4,5-methylenedioxyphenyl)-3,4-dihydro-quinazolin-2(1h)-one

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Reaction Steps

This compound was synthesized from N-isopropyl-N-[3,4-(methylenedioxy)-phenyl]urea (410 mg) and 6-chloropiperonal (350 mg) by the procedure described in example 10 in 65% yield. 1H NMR (CDCl3): 6.86 (s, 1H), 6.77 (s, 1H), 6.48 (s, 1H), 6.40 (s, 1H), 5.95 (s, 4H), 5.66 (d, J=2.5, 1H), 5.21 (s, 1H), 4.48 (m, 1H), 1.53 (d, J=6.5, 6H).

Provenance & Evidence