Tetrahydrofuran → 2-(4-{4-[7-amino-2-(isoquinolin-5-yl)furo[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}piperidin-1-yl)ethanol
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH2:8][N:9]1[CH2:10][CH2:11][CH:12]([n:15]2[n:16][cH:17][c:18](-[c:20]3[c:21]4[c:22]([c:23]([NH2:26])[n:24][cH:25]3)[o:27][c:28](-[c:30]3[c:31]5[cH:32][cH:33][n:34][cH:35][c:36]5[cH:37][cH:38][cH:39]3)[cH:29]4)[cH:19]2)[CH2:13][CH2:14]1)([CH3:5])([CH3:40])[CH3:41].[CH2:43]([N+:44]([CH2:45][CH2:46][CH2:47][CH3:48])([CH2:49][CH2:50][CH2:51][CH3:52])[CH2:53][CH2:54][CH2:55][CH3:56])[CH2:57][CH2:58][CH3:59].[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[F-:42]>>[OH:6][CH2:7][CH2:8][N:9]1[CH2:10][CH2:11][CH:12]([n:15]2[n:16][cH:17][c:18](-[c:20]3[c:21]4[c:22]([c:23]([NH2:26])[n:24][cH:25]3)[o:27][c:28](-[c:30]3[c:31]5[cH:32][cH:33][n:34][cH:35][c:36]5[cH:37][cH:38][cH:39]3)[cH:29]4)[cH:19]2)[CH2:13][CH2:14]1Participants
5
Sources & evidence
- ORD record
- ord-ef6befeb6dae4f2c988f2facde6f240a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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