Methanol → 4-(trans-4-Hydroxycyclohexyl)-1-methylpiperazin-2-one

HRID 99159Notes

Reaction equation

HRID 99159 reaction equation
[CH3:21][S:22](=[O:23])(=[O:24])[OH:25].[CH3:28][OH:29].[Na+:27].[OH-:26].[OH2:20].[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][CH2:9][C:10](=[O:11])[N:12]([CH3:13])[CH2:14][CH:15]([O:16][CH3:17])[O:18][CH3:19])[CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([N:8]2[CH2:9][C:10](=[O:11])[N:12]([CH3:13])[CH2:14][CH2:15]2)[CH2:6][CH2:7]1

Participants

7

Reactant 6

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6395Methanesulfonic AcidHCID 59158221(trans)-1-hydroxy-4-{[N-(2,2-dimethoxy-ethyl)-N-methyl-amino]-carbonylmethylamino}-cyclohexane

Product 1

HCID 534025914-(trans-4-Hydroxycyclohexyl)-1-methylpiperazin-2-one

Sources & evidence

ORD record
ord-7ec0949e3d5c4e71909456328f1fa733
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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