HCID 22036340, compound → HCID 131723546, compound

HRID 991601Notes

Reaction equation

HRID 991601 reaction equation
[Cl:1][C:2]1[C:11]([O:12][CH2:13][CH2:14][O:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1>O>[ClH:1].[O:15]([CH2:14][CH2:13][O:12][C:11]1[C:2]([N:3]2[CH2:4][CH2:9][NH:10][CH2:11][CH2:2]2)=[N:3][C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[N:10]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 1

HCID 22036340HCID 22036340, compound

Product 1

HCID 131723546HCID 131723546, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The title compound was prepared according to the procedure described in Example 1, Step 2, starting from 2-chloro-3-(2-phenoxyethoxy)quinoxaline (0.65 g, 2.15 mmol): yield 0.44 g (58%) as the free base. A portion of the free base was converted to its hydrochloride salt: mp 123-126° C.; HRMS m/z calcd for C20H22N4O2 (M)+ 350.1743, found 350.1748. Anal. (C20H22N4O2 1.75 HCl. 0.5 H2O) C, H, N.

Sources & evidence

ORD record
ord-e124e205dfee4233a086b467048cb21f
Source dataset
uspto-grants-2002_10
Patent number
US06465467B1

Reaction notes

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