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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 991758생성일: 2026년 10월 26일

Methyl 2-Carbobenzyloxyamino-3-(4-tert-butoxycarbonylpiperazin-1-yl)propionate → Methyl 2-Amino-3-(4-tert-butoxycarbonylpiperazin-1-yl)propionate

https://huagongshe.com/reaction/991758

반응식

참여 물질

역할이름HCID투입량
반응물Methyl 2-Carbobenzyloxyamino-3-(4-tert-butoxycarbonylpiperazin-1-yl)propionateHCID 21940471—
반응물HCID 178418361HCID 178418361—
용매MethanolHCID 887—
용매PalladiumHCID 23938—
생성물Methyl 2-Amino-3-(4-tert-butoxycarbonylpiperazin-1-yl)propionateHCID 21940545—

반응 단계

The title material from Step A was dissolved in methanol with catalytic amount of 10% Pd on C. The reaction mixture was hydrogenated for 2 hours at room temperature in methanol under 25 psi of hydrogen. After filtration of the crude reaction mixture through a pad of Celite, the solvent was evaporated under reduced pressure to afford the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06465513B1
출처 데이터셋uspto-grants-2002_10
ORD IDord-c18e748494f643b8b41d754325ee1c26
출처 메모uspto-grants-2002_10