HCID 12967140, compound → Tert-butyl 6-oxo-1,2,3,6-tetrahydropyridine-1-carboxylate

Participants

Reaction Steps

3-Benzenesulfonyl-2-oxo-piperidine-1-carboxylic acid tert-butyl ester from above in toluene (50 mL) was heated at 80° C. for one hour. The reaction mixture was concentrated and the resulting oil was purified by column chromatography (20-30% EtOAc in Hexane) to give 2 g of 6-oxo-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester as an oil.

Provenance & Evidence