Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde | HCID 9964189 | — |
| Reactant | 4-(2-Hydroxyethyl)indolin-2-one | HCID 10943004 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 49823033 | HCID 49823033 | — |
Reaction Steps
A mixture of 4-(2-hydroxy-ethyl)-1,3-dihydro-indol-2-one (35.4 mg, 0.2 mmol), 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (32.8 mg, 0.2 mmol) and 0.1 mL of piperidine in ethanol (1 mL) was heated in a sealed tube at 80° C. for 4 hours. The precipitate was collected by vacuum filtration, washed with cold ethanol and dried to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06465507B2 |
|---|
| Source dataset | uspto-grants-2002_10 |
|---|
| ORD ID | ord-7c5c0535f17f420fbdaece4808518ff6 |
|---|
| Source note | uspto-grants-2002_10 |
|---|
