Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde | HCID 9964189 | — |
| Reactant | 2-Oxoindoline-5-sulfonamide | HCID 10198232 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 69708048 | HCID 69708048 | 82.8% |
Reaction Steps
A mixture of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide (63 mg, 0.3 mmol), 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (50 mg, 0.3 mmol) and 0.1 mL of piperidine in ethanol (1 mL) was heated in a sealed tube at 80° C. for 4 hours. The precipitate was collected by vacuum filtration, washed with cold ethanol and dried to give 89 mg (82%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06465507B2 |
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| Source dataset | uspto-grants-2002_10 |
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| ORD ID | ord-b897164b77e84ad0bc2f746975566202 |
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| Source note | uspto-grants-2002_10 |
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