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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 991845Generated: October 31, 2026

Piperidine → HCID 69708048, compound

https://huagongshe.com/reaction/991845

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehydeHCID 9964189—
Reactant2-Oxoindoline-5-sulfonamideHCID 10198232—
SolventEthanolHCID 702—
ProductHCID 69708048HCID 6970804882.8%

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide (63 mg, 0.3 mmol), 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (50 mg, 0.3 mmol) and 0.1 mL of piperidine in ethanol (1 mL) was heated in a sealed tube at 80° C. for 4 hours. The precipitate was collected by vacuum filtration, washed with cold ethanol and dried to give 89 mg (82%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06465507B2
Source datasetuspto-grants-2002_10
ORD IDord-b897164b77e84ad0bc2f746975566202
Source noteuspto-grants-2002_10