HRID991966

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8003

Pentane

C5H12

结构：Cc1ccc(P(c2ccc(C)cc2)c2ccc3ccccc3c2-c2c(P(c3ccc(C)cc3)c3ccc(C)cc3)ccc3ccccc23)cc1

HCID4189906

1,1′-[[1,1′-Binaphthalene]-2,2′-diyl]bis[1,1-bis(4-methylphenyl)phosphine

C48H40P2

HCID11829917

未命名化合物

PRODUCTS

生成物

HCID14400119

未命名化合物

收率 795.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

General procedure B using (S)-p-tol-BINAP and 3-benzylcyclopentenone (0.11 g, 0.7 mmol) gave, after 24 h at 0° C. and flash chromatography (6:1 pentane:diethyl ether), the title compound as a clear liquid (0.97 g, 85% yield). Spectroscopic data were consistent with previously reported data for this compound.12 [α]D25° C.−96° (c 1.3, CHCl3). Chiral HPLC analysis (Chiracel OD column) indicated that the title compound was obtained in 96% ee.

WORKUP

后处理

customgave, after 24 h at 0° C.