HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Pyrrolo(2,3-b)pyridine → 3-(1,4-Dioxa-spiro[4,5]dec-7-en-8-yl)-1H-azaindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Pyrrolo(2,3-b)pyridine | HCID 9222 | — |
| Reactant | 3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-1H-indole | HCID 2763857 | — |
| Product | 3-(1,4-Dioxa-spiro[4,5]dec-7-en-8-yl)-1H-azaindole | HCID 18414101 | 68% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 1a by replacing indole with 7-azaindole (3.65 g, 31 mmol) in 68% yield (5.42 g) as a white solid: mp 162-165° C.; MS EI m/e 256 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465482B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-8e38bfc1c69f4b77b0ae96550d23bff5 |
| Source note | uspto-grants-2002_10 |