HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1,4-Dioxa-spiro[4,5]dec-7-en-8-yl)-5-fluoro-1H-indole → 4-(5-Fluoro-1H-3-indolyl)-cyclohex-3-enone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1,4-Dioxa-spiro[4,5]dec-7-en-8-yl)-5-fluoro-1H-indole | HCID 10516380 | — |
| Reactant | 4-(5-Fluoro-1H-indol-3-YL)cyclohexanone | HCID 10704683 | — |
| Product | 4-(5-Fluoro-1H-3-indolyl)-cyclohex-3-enone | HCID 18414096 | 88% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 3c by replacing 4-(5-fluoro-1H-3-indolyl)-cyclohexanone ethylene ketal with 4-(5-fluoro-1H-3-indolyl)-cyclohex-3-enone-ethylene ketal (1.37 g) to afford 1.01 g (88%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465482B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-c4646cb54d5248fb8a957bfe2cebe7d4 |
| Source note | uspto-grants-2002_10 |