HCID 54131529, compound → HCID 18411541, compound

HRID 992204Notes

Reaction equation

HRID 992204 reaction equation
[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[C:6]1[N:7]=[C:8]([CH2:11][OH:12])[S:9][CH:10]=1>C(Cl)Cl.CO.O=[Mn]=O>[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[C:6]1[N:7]=[C:8]([CH:11]=[O:12])[S:9][CH:10]=1

Participants

5

Reactant 1

HCID 54131529HCID 54131529, compound

Product 1

HCID 18411541HCID 18411541, compound

Reagents, catalysts & solvents 3

HCID 14801Manganese dioxideCatalystHCID 887MethanolSolventHCID 6344DichloromethaneSolvent

Procedure

A mixture of [2,4′]bithiazol-2′-ylmethanol (1.53 g; 7.72 mmol), obtained as described in the above step, and MnO2 (13.93 g; 160.2 mmol) in CH2Cl2 (76.5 ml) and methanol (7.65 ml) was stirred at room temperature for about 23 hours.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-eb742919384d4db18d602df05edb5984
Source dataset
uspto-grants-2002_10
Patent number
US06468979B1

Reaction notes

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