2,2-Diethoxythioacetamide → 4-(3-Methylisoxazol-5-yl)thiazole-2-carbaldehyde

HRID 992208노트

반응식

HRID 992208 반응식
C(O[CH:4]([O:8]CC)[C:5]([NH2:7])=[S:6])C.Br[CH2:12][C:13]([C:15]1[O:19][N:18]=[C:17]([CH3:20])[CH:16]=1)=O>C(O)C>[CH3:20][C:17]1[CH:16]=[C:15]([C:13]2[N:7]=[C:5]([CH:4]=[O:8])[S:6][CH:12]=2)[O:19][N:18]=1

참가 물질

4

반응물 2

HCID 27947342,2-DiethoxythioacetamideHCID 148146892-Bromo-1-(3-methylisoxazol-5-yl)ethanone

생성물 1

HCID 184115504-(3-Methylisoxazol-5-yl)thiazole-2-carbaldehyde

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of diethoxythioacetamide (6.65 g; 0.04077 mol) and 2-bromo-1-(3-methylisoxazol-5-yl)ethanone (10 g; 0.04077 mol), prepared as described in the above step, in absolute ethanol (31.3 ml) was kept overnight at room temperature and then refluxed for 30 minutes.

후처리

  1. temperaturerefluxed for 30 minutes

출처 및 근거

ORD 기록
ord-6518dabbb5744facbae7e3e3e5784d65
출처 데이터셋
uspto-grants-2002_10
특허 번호
US06468979B1

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