HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Diethoxythioacetamide → 4-(3-Methylisoxazol-5-yl)thiazole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Diethoxythioacetamide | HCID 2794734 | — |
| Reactant | 2-Bromo-1-(3-methylisoxazol-5-yl)ethanone | HCID 14814689 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(3-Methylisoxazol-5-yl)thiazole-2-carbaldehyde | HCID 18411550 | — |
Reaction Steps
A solution of diethoxythioacetamide (6.65 g; 0.04077 mol) and 2-bromo-1-(3-methylisoxazol-5-yl)ethanone (10 g; 0.04077 mol), prepared as described in the above step, in absolute ethanol (31.3 ml) was kept overnight at room temperature and then refluxed for 30 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06468979B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-6518dabbb5744facbae7e3e3e5784d65 |
| Source note | uspto-grants-2002_10 |