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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 992297Generated: October 25, 2026

Dicyclohexylacetic acid → (S)-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)dicyclohexylacetamide

https://huagongshe.com/reaction/992297

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDicyclohexylacetic acidHCID 3661562—
Reactant(S)-3-amino-1-(2-(4-fluorophenyl)ethyl)pyrrolidineHCID 59915932—
Product(S)-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)dicyclohexylacetamideHCID 5991590326.5%

Reaction Steps

Dicyclohexylacetic acid (0.45 g) and (S)-3-amino-1-(2-(4-fluorophenyl)ethyl)pyrrolidine (0.42 g) were reacted under the same conditions as in Example 23 to give (S)-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)dicyclohexylacetamide (0.22 g), melting point 122-124° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06468998B1
Source datasetuspto-grants-2002_10
ORD IDord-12b5a980701045a28b9a9d228ac359c4
Source noteuspto-grants-2002_10