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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 992312Generated: November 2, 2026

1-Adamantanecarbonyl chloride → N-phenyl-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)-1-adamantanecarboxamide

https://huagongshe.com/reaction/992312

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Adamantanecarbonyl chlorideHCID 98915—
Reactant3-Anilino-1-(2-(4-fluorophenyl)ethyl)pyrrolidineHCID 18411931—
ProductN-phenyl-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)-1-adamantanecarboxamideHCID 18411836—

Reaction Steps

3-Anilino-1-(2-(4-fluorophenyl)ethyl)pyrrolidine and 1-adamantanecarbonyl chloride were reacted under the same conditions as in Example 53 to give N-phenyl-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)-1-adamantanecarboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06468998B1
Source datasetuspto-grants-2002_10
ORD IDord-314477ff033d42159d5787b3f5fe0f5e
Source noteuspto-grants-2002_10