Tetrahydrofuran → N-(1-(2-Bromo-4-fluorophenyl)ethyl)-2,2-difluoroethanamine

HRID 99234Notes

Reaction equation

HRID 99234 reaction equation
[Br:1][c:2]1[c:3]([CH:9]([CH3:10])[NH:11][C:12]([CH:13]([F:14])[F:15])=[O:16])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[CH2:17]1[O:18][CH2:19][CH2:20][CH2:21]1>>[Br:1][c:2]1[c:3]([CH:9]([CH3:10])[NH:11][CH2:12][CH:13]([F:14])[F:15])[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

3

Reactant 2

HCID 8028TetrahydrofuranHCID 57445093N-(1-(2-Bromo-4-fluorophenyl)ethyl)-2,2-difluoroacetamide

Product 1

HCID 86640661N-(1-(2-Bromo-4-fluorophenyl)ethyl)-2,2-difluoroethanamine

Sources & evidence

ORD record
ord-dc509aa0c01f433a9aee91fdc57ad16c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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