HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-1-(2-Phenylethyl)-3-pyrrolidinamine → (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-1-azabicyclo[2.2.2]octane-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-1-(2-Phenylethyl)-3-pyrrolidinamine | HCID 10774056 | — |
| Reactant | 1-Azabicyclo[2.2.2]octane-4-carbonyl chloride | HCID 13760940 | — |
| Product | (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-1-azabicyclo[2.2.2]octane-4-carboxamide | HCID 22888074 | — |
Reaction Steps
1-Azabicyclo[2.2.2]octane-4-carbonyl chloride and (S)-3-amino-1-(2-phenylethyl)pyrrolidine were reacted under the same conditions as in Example 53 to give (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-1-azabicyclo[2.2.2]octane-4-carboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06468998B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-b9005c185528441c8289d14214815d8e |
| Source note | uspto-grants-2002_10 |