Iodoethane → 1-Ethyl-4-(4-phenoxyphenyl)piperidine

HRID 992375Notes

Reaction equation

HRID 992375 reaction equation
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:20](I)[CH3:21]>>[CH2:20]([N:17]1[CH2:18][CH2:19][CH:14]([C:11]2[CH:12]=[CH:13][C:8]([O:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)=[CH:9][CH:10]=2)[CH2:15][CH2:16]1)[CH3:21]

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 110759844-(4-Phenoxyphenyl)piperidine

Product 1

HCID 187944781-Ethyl-4-(4-phenoxyphenyl)piperidine

Procedure

The same procedure was followed as in Example 11 using the compound (9) synthesized in Example 2 and ethyl iodide to produce the above.

Workup

  1. customto produce the above

Sources & evidence

ORD record
ord-c518027054d74f4892c74b4db4f7043e
Source dataset
uspto-grants-2002_10
Patent number
US06469010B1

Reaction notes

Loading…