Dichloromethane → 8-bromo-N-(2,4-difluorophenyl)-N-methyl-4H-thieno[3,2-c]chromene-2-carboxamide

HRID 99268Notes

Reaction equation

HRID 99268 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[O:8][CH2:7][c:6]1[c:5]-2[s:14][c:13]([C:15](=[O:16])[Cl:17])[cH:12]1.[CH3:18][NH:19][c:20]1[c:21]([F:27])[cH:22][c:23]([F:26])[cH:24][cH:25]1.[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[Cl:35][CH2:36][Cl:37]>>[Br:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[O:8][CH2:7][c:6]1[c:5]-2[s:14][c:13]([C:15](=[O:16])[N:19]([CH3:18])[c:20]2[c:21]([F:27])[cH:22][c:23]([F:26])[cH:24][cH:25]2)[cH:12]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 27370232,4-difluoro-N-methylanilineHCID 579004048-bromo-4H-thieno[3,2-c]chromene-2-carbonyl chloride

Product 1

HCID 579003378-bromo-N-(2,4-difluorophenyl)-N-methyl-4H-thieno[3,2-c]chromene-2-carboxamide

Sources & evidence

ORD record
ord-b1a9424f18c44a9daeec460e2a8d3b4c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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